Gold Member Since 2017 
Audited Supplier
| Reference FOB Price: | US $2.50-4.50 / G |
|---|---|
| Min. Order: | 5 G |
| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Adult |
| State: | Solid |
| Purity: | 98-99% |
Product | Tianeptine CAS 66981-73-5 | |
Perform standard | Enterprise standard | |
Items | Specifications | Results |
Appearance | White or almost white microcrystalline powder | White powder |
Solubility | Insoluble in the water and methanol | Complies |
Identification | Should comply | Complies |
Related substance | Individual impurity: Not more than0.1% | 0.06% |
| Total impurities: Not more than 0.5% | 0.13% |
Residue on ignation | Not more than 0.2% | 0.02% |
Loss on drying | Not more than 1.0% | 0.09% |
Heavy metal | Not more than 20ppm | < 20ppm |
Assay (on anhydrous basis) | Not less than 99.0% | 99.35% |
Tianeptine Acid is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Function of Tianeptine Acid
Tianeptine acid has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
